Though I can't say we've done that yet, we've played with *existing* friends, cousins and siblings and it's been a riot! My new favorite party game ever.
The idea is very simple, one person picks two premise cards, and each player has to lay a few cards down to come up with an anime title to fit the premise. The kicker is - you then have to explain your anime!! We have house rules so that the person who picked the premise picks the round winner, but I think the actual rules is a vote or something.
The best one we had so far - the premise was fanservice car racing or something like that. My sister threw down "blue tsubasa twins", which has nothing to do with anything, but her story was so complex! Something about the revenge of a dead father in which the beautiful twins have to drive into space. I've requested fan art already.
And for you non-otaku, there are definitions on some of the more niche cards, which is nice.
Anyway, I love this game, and can't wait to bring it to fanime with me to try out with Cousin T. Or maybe I'll find some courage and make a new friend. Ha! :P